发明名称 ANTICANCER AGENT
摘要 PROBLEM TO BE SOLVED: To obtain an anticancer agent having broad antitumor spectra by including a specific compound having a hydronaphthalene ring structure as an active ingredient. SOLUTION: This medicine has a hydronaphthalene ring structure which may possess an unsaturated linkage represented by the formula [R<1> -R<3> are each a (substituted) alkyl] and includes a compound in which the structure derived from isocitric acid is not combined with the methyloxy group in the 9-position of the naphthalene ring through ether linkage as an active ingredient. As the above compound, sclareol, sclareolide, manool or the like is preferably used. On the effective dose, it is favorable to be administrated once or several times a day at a dosage of preferably 0.1-100 mg/kg weight/day.
申请公布号 JPH11349478(A) 申请公布日期 1999.12.21
申请号 JP19980170700 申请日期 1998.06.03
申请人 TOAGOSEI CO LTD 发明人 NOZOE SHIGEO;TAKAHASHI AKIRA;MASUDA JUNICHI;KANO MUNEAKI;TANAKA KENICHI;WAKAYAMA TOSHIYUKI;KOIKE NOBUAKI;UCHIDA TAKAYOSHI;OTA YOSHIAKI;NAGATA TOSHIYUKI;SEGAWA TOSHIAKI
分类号 C07D249/08;A61K31/045;A61K31/047;A61K31/075;A61K31/13;A61K31/165;A61K31/19;A61K31/215;A61K31/27;A61K31/335;A61K31/336;A61K31/357;A61K31/40;A61K31/41;A61K31/415;A61K31/443;A61K31/445;A61K31/495;A61K31/535;A61K31/5375;A61K31/70;A61K31/7028;A61P35/00;C07D207/16;C07D233/61;C07D265/30;C07D295/08;C07D295/12;C07D303/24;C07D317/72;C07D405/10;C07H15/18 主分类号 C07D249/08
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