发明名称 |
MICROCRYSTALLINE CELLULOSE SPHERONIZATION COMPOSITION |
摘要 |
A particulate co-processed unattrited microcrystalline cellulose: hydrocolloid composition wherein the respective components are present in a weight ratio of from about 99:1 to 70:30. The composition is useful as a spheronizing agent for producing spheroids of uniform size and sphericity and having high drug loadings. The composition is produced by drying a slurry of the microcrystalline cellulose in an aqueous solution of the hydrocolloid. The preferred hydrocolloid is methyl cellulose.
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申请公布号 |
CA2126441(C) |
申请公布日期 |
1999.12.21 |
申请号 |
CA19922126441 |
申请日期 |
1992.11.18 |
申请人 |
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发明人 |
ERKOBONI, DAVID F.;FIORE, SCOTT A.;WHEATLEY, THOMAS A. |
分类号 |
A61K9/14;A61K9/16;A61K47/40;C08J3/00;C08L1/00;C08L1/02;C08L1/08;C08L1/28;(IPC1-7):A61K47/38;A61K9/20 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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