| 发明名称 |
Use of von willebrand factor and pharmaceutical formulation |
| 摘要 |
The invention relates to the use of von Willebrand Factor (vWF) with a prolonged biological half-life for the production of a preparation for stabilization of blood coagulation Factor VIII (FVIII:C) in a mammal. Additionally, a pharmaceutical preparation is provided comprising a biologically active FVIII:C/vWF complex with improved pharmokinetic properties, said complex containing a vWF with a prolonged biological half-life.
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| 申请公布号 |
US6005077(A) |
申请公布日期 |
1999.12.21 |
| 申请号 |
US19960744646 |
申请日期 |
1996.11.06 |
| 申请人 |
IMMUNO AKTIENGESELLSCHAFT;BAXTER AG |
发明人 |
SCHWARZ, HANS-PETER;TURECEK, PETER;EIBL, JOHANN |
| 分类号 |
G01N33/53;A61K38/00;A61K38/43;A61P7/00;A61P7/04;C07K14/745;C07K14/755;G01N33/86;(IPC1-7):A61K35/14 |
主分类号 |
G01N33/53 |
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