发明名称 |
Staphylococcus aureus RSBU-1 |
摘要 |
rsbU-1 polypeptides and DNA (RNA) encoding such rsbU-1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such rsbU-1 for the treatment of infection, particularly bacterial infections. Antagonists against such rsbU-1 and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of rsbU-1 nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and for detecting the polypeptide in a host.
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申请公布号 |
US6004556(A) |
申请公布日期 |
1999.12.21 |
申请号 |
US19970938546 |
申请日期 |
1997.09.26 |
申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
FOSBERRY, ANDREW P;LAWLOR, ELIZABETH J;NICHOLAS, RICHARD O |
分类号 |
G01N33/53;A61K38/00;A61K39/085;A61K39/395;A61K48/00;A61P1/00;A61P11/00;A61P13/02;A61P15/00;A61P25/00;A61P27/02;A61P29/00;A61P31/04;C07K2/00;C07K14/31;C12N15/09;C12N15/31;C12Q1/68;(IPC1-7):A61K39/085;A61K31/70;C07H21/04;C12P21/02 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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