摘要 |
FIELD: medicine, pharmacy. SUBSTANCE: invention claims thrombolytic agent activating fibrinolysis, the use of 6-amidino-2-naphthyl-4-[(4,5-dihydro-1H-imidazole- -2-yl)-amino]-benzoate or its pharmaceutically acceptable acid addition salts of the formula (I) as indicated agents and methods of treatment of patients with thrombosis and myocardium infarction. Agents showing thrombolytic and effect activating fibrinolysis have effective amount of the compound of the formula (I). Methods of patient treatment involve administration to patient an effective amount of an agent. Agents can contain pharmaceutically acceptable carriers additionally. The claimed agents and methods of patient treatment ensure to dissolve thrombi in blood vessels and so eliminate their obstruction. Agents can be administrated orally that makes advantages as compared with the known preparations of similar effect administrated into blood vessel by catheter. EFFECT: enhanced effectiveness of agents. 12 cl, 3 dwg, 2 tbl, 9 ex |