| 发明名称 |
DERIVATIVES OF PYRAZOLE AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF |
| 摘要 |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes new derivatives of pyrazole of the general formula (I) <EMI ID=0.437 HE=30 WI=27 TI=CHI> given in p. 1 of the invention claim. Compounds show an antagonistic activity with respect to corticotropin releasing-factor. They are effective for treatment of patients with broad pattern of diseases including diseases induced by stress. Invention describes also a pharmaceutical composition based on the above indicated compounds. EFFECT: enhanced effectiveness of derivatives and compositions. 7 cl, 2 tbl, 18 ex |
| 申请公布号 |
RU2142946(C1) |
申请公布日期 |
1999.12.20 |
| 申请号 |
RU19950113969 |
申请日期 |
1993.11.03 |
| 申请人 |
PFAJZER INK. |
发明人 |
UIL'JAM STIVEN FARASI;UILLARD MAKKOVAN UEHLCH |
| 分类号 |
A61K31/415;A61K31/505;A61P1/00;A61P25/24;A61P25/26;A61P25/28;A61P29/00;A61P37/06;C07D231/18;C07D231/38;C07D231/44;C07D231/52;C07D403/04;C07D403/10;C07D409/06;C07D409/10;C07D487/04 |
主分类号 |
A61K31/415 |
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