| 发明名称 |
NOVEL THERAPEUTIC AGENTS THAT MODULATE ENZYMATIC PROCESSES |
| 摘要 |
Novel multi-binding compounds are disclosed that modulate enzymatic processes. The compounds of the invention comprise from 2-10 ligands covalently connected, each of said ligands being capable of binding to an enzyme, enzyme substrate or enzyme cofactor thereby modulating the biological processes/functions thereof.
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| 申请公布号 |
CA2321190(A1) |
申请公布日期 |
1999.12.16 |
| 申请号 |
CA19992321190 |
申请日期 |
1999.06.08 |
| 申请人 |
ADVANCED MEDICINE, INC. |
发明人 |
GRIFFIN, JOHN H.;JUDICE, J. KEVIN |
| 分类号 |
C07D499/44;A01N57/34;A61K31/00;A61K31/357;A61K31/397;A61K31/407;A61K31/421;A61K31/424;A61K31/431;A61K31/439;A61K31/444;A61K31/4545;A61K31/496;A61K31/522;A61K31/536;A61K31/5377;A61K31/546;A61K31/551;A61K31/65;A61K31/7028;A61K31/7034;A61K31/7036;A61K31/7042;A61K31/7048;A61K31/7052;A61K31/7056;A61K31/7064;A61K31/7068;A61K31/7072;A61K38/00;A61K39/00;A61K39/395;A61K39/44;A61K47/48;A61K51/00;A61P31/04;A61P31/18;A61P43/00;C07B61/00;C07C233/36;C07C233/78;C07C237/24;C07C237/26;C07C271/20;C07C275/42;C07C321/04;C07C323/12;C07C335/08;C07C335/32;C07D207/32;C07D207/333;C07D211/58;C07D215/56;C07D233/90;C07D235/30;C07D263/28;C07D265/18;C07D401/06;C07D401/12;C07D401/14;C07D405/04;C07D413/14;C07D453/02;C07D471/04;C07D471/14;C07D473/00;C07D473/34;C07D475/04;C07D475/08;C07D477/00;C07D487/04;C07D487/06;C07D493/04;C07D493/06;C07D495/04;C07D498/04;C07D498/18;C07D501/20;C07D519/00;C07H15/236;C07H15/238;C07H15/26;C07H17/08;C07H19/06;C07H19/20;C07K2/00;C07K4/00;C12N9/99;C12P19/38;C12Q1/26;C12Q1/44;C12Q1/48;C12Q1/533;C40B30/04;C40B40/04;G01N33/15;G01N33/50;G01N33/53;G01N33/543;G01N33/566;G01N33/573;G01N33/68;G01N33/92;G01N37/00;(IPC1-7):A61K31/00 |
主分类号 |
C07D499/44 |
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