INHIBITORS OF H<+>K<+>-ATPase,申请号WO1999US12925-传众专利搜索

发明名称	INHIBITORS OF H<+>K<+>-ATPase
摘要	Disclosed are multibinding compounds which inhibit H<+>/K<+>-ATPase, an enzyme which is involved in the control of acid secretion in the stomach. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is an inhibitor of H<+>/K<+>-ATPase. The multibinding compounds of this invention are useful in the treatment gastroesophageal reflux disease ("GERD").
申请公布号	WO9963940(A2)	申请公布日期	1999.12.16
申请号	WO1999US12925	申请日期	1999.06.08
申请人	ADVANCED MEDICINE, INC.;MEIER-DAVIS, SUSAN;GRIFFIN, JOHN, H.;CHOI, SEOK-KI	发明人	MEIER-DAVIS, SUSAN;GRIFFIN, JOHN, H.;CHOI, SEOK-KI
分类号	C07D499/44;A01N57/34;A61K31/00;A61K31/357;A61K31/397;A61K31/407;A61K31/421;A61K31/424;A61K31/431;A61K31/439;A61K31/444;A61K31/4545;A61K31/496;A61K31/522;A61K31/536;A61K31/5377;A61K31/546;A61K31/551;A61K31/65;A61K31/7028;A61K31/7034;A61K31/7036;A61K31/7042;A61K31/7048;A61K31/7052;A61K31/7056;A61K31/7064;A61K31/7068;A61K31/7072;A61K38/00;A61K39/00;A61K39/395;A61K39/44;A61K47/48;A61K51/00;A61P31/04;A61P31/18;A61P43/00;C07B61/00;C07C233/36;C07C233/78;C07C237/24;C07C237/26;C07C271/20;C07C275/42;C07C321/04;C07C323/12;C07C335/08;C07C335/32;C07D207/32;C07D207/333;C07D211/58;C07D215/56;C07D233/90;C07D235/30;C07D263/28;C07D265/18;C07D401/06;C07D401/12;C07D401/14;C07D405/04;C07D413/14;C07D453/02;C07D471/04;C07D471/14;C07D473/00;C07D473/34;C07D475/04;C07D475/08;C07D477/00;C07D487/04;C07D487/06;C07D493/04;C07D493/06;C07D495/04;C07D498/04;C07D498/18;C07D501/20;C07D519/00;C07H15/236;C07H15/238;C07H15/26;C07H17/08;C07H19/06;C07H19/20;C07K2/00;C07K4/00;C12N9/99;C12P19/38;C12Q1/26;C12Q1/44;C12Q1/48;C12Q1/533;C40B30/04;C40B40/04;G01N33/15;G01N33/50;G01N33/53;G01N33/543;G01N33/566;G01N33/573;G01N33/68;G01N33/92;G01N37/00	主分类号	C07D499/44
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