发明名称 HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS
摘要 Compounds of Formula (I) are antagonists of VLA-4 and/or alpha 4 beta 7, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical compositions and are suitable for use in the treatment of asthma, allergies, inflammation, multiple sclerosis, and other inflammatory and autoimmune disorders.
申请公布号 WO9964395(A1) 申请公布日期 1999.12.16
申请号 WO1998US11623 申请日期 1998.06.11
申请人 MERCK & CO., INC. 发明人 DURETTE, PHILIPPE, L.;HAGMANN, WILLIAM, K.;MACCOSS, MALCOLM;MILLS, SANDER, G.;MUMFORD, RICHARD, A.;VAN RIPER, GAIL, A.;SCHMIDT, JACK, A.;KEVIN, NANCY, J.
分类号 A61K31/401;A61K31/445;A61K31/472;A61K45/06;C07D205/04;C07D207/48;C07D209/42;C07D211/96;C07D217/26;C07D277/06;C07D401/06;C07D401/12;C07D403/12;C07D405/06;C07D409/12;C07D409/14;C07D417/12;C07D417/14;C07D493/10;C07D495/04;(IPC1-7):C07D207/04;C07D211/06;C07D217/06;C07D277/02;A61K31/40;A61K31/47;A61K31/425 主分类号 A61K31/401
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