| 摘要 |
<p>Disclosed are novel multi-binding compounds (agents) which bind 5-HT3 receptors. The compounds of this invention comprise a plurality of ligands each of which can bind to such receptors thereby modulating the biological processes/functions thereof. Each of the ligands is covalently attached to a linker or linkers which may be the same or different to provide for the multi-binding compound. The linker is selected such that the multi-binding compound so constructed demonstrates increased modulation of the biological processes mediated by the 5-HT3 receptor.</p> |
