| 发明名称 |
Serine protease inhibitors-N-substituted derivatives |
| 摘要 |
The present invention relates to oxadiazole, thiadiazole, and triazole peptoids that are inhibitors of serine protease, specifically human neutrophil elastase; which proteases are useful in treatment of adult respiratory distress syndrome, septic shock, and multiple organ failure.
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| 申请公布号 |
US6001811(A) |
申请公布日期 |
1999.12.14 |
| 申请号 |
US19970984884 |
申请日期 |
1997.12.04 |
| 申请人 |
CORTECH INC. |
发明人 |
GYORKOS, ALBERT;SPRUCE, LYLE W. |
| 分类号 |
A61K38/00;C07D271/10;C07D413/12;C07D413/14;C07D417/12;C07K5/02;C07K5/06;C07K5/062;C07K5/065;C07K5/068;C07K5/072;C07K5/078;C07K5/083;C07K5/12;(IPC1-7):A61K38/05;A61K38/06;C07K5/08 |
主分类号 |
A61K38/00 |
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