| 发明名称 |
Chemokine NC28 (monocyte chemotactic protein-3, MCP-3) polypeptides and their recombinant production |
| 摘要 |
PCT No. PCT/FR91/00949 Sec. 371 Date Sep. 29, 1992 Sec. 102(e) Date Sep. 29, 1992 PCT Filed Nov. 29, 1990 PCT Pub. No. WO92/09629 PCT Pub. Date Jun. 11, 1992A new chemotactic cytokine, NC28 or Monocyte Chemotactic Protein-3 (MCP-3), is provided. Fragments of the cytokine comprising its 13 C-terminal amino acids also exhibit chemotactic activity. The polypeptides may be used as anticancer agents or immunomodulators. DNA encoding the NC28/MCP-3 polypeptides, as well as corresponding vectors and recombinant expression systems, are also provided.
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| 申请公布号 |
US6001649(A) |
申请公布日期 |
1999.12.14 |
| 申请号 |
US19920927391 |
申请日期 |
1992.09.29 |
| 申请人 |
SOCIETE ANONYME: ELF SANOFI |
发明人 |
CAPUT, DANIEL;FERRARA, PASCUAL;MILOUX, BRIGITTE;MINTY, ADRIAN;VITA, NATALIO |
| 分类号 |
A61K38/00;A61P35/00;A61P37/00;C07K14/52;C07K19/00;C12N1/19;C12N5/10;C12N15/00;C12N15/09;C12N15/19;C12P21/02;C12R1/865;C12R1/91;(IPC1-7):C12N15/19 |
主分类号 |
A61K38/00 |
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