发明名称 |
GROWTH HORMONE FUSION PROTEINS |
摘要 |
A plasmid encoding a fusion protein comprising a first polypeptide having growth hormone activity and a second polypeptide which may be one of insulin growth factor (1GF)-I, or IGF-II and their analogues, chicken histone H2A.I or human transcription factor SPI-lac Z with an optional cleavage sequence between the first and second polypeptides. The fusion protein may be used: 1) to treat growth hormone deficiencies; 2) to suppress loss of body protein following trauma such as burns or infection; 3) for farm animals to increase growth rates and efficiency of food conversion; 4) and to support growth of cells in culture.
|
申请公布号 |
CA2033176(C) |
申请公布日期 |
1999.12.14 |
申请号 |
CA19902033176 |
申请日期 |
1990.05.22 |
申请人 |
|
发明人 |
WELLS, JULIAN RICHARD ESTE;KING, ROBERT MICHAEL;FRANCIS, GEOFFREY LEONARD |
分类号 |
A61K38/00;C07K14/465;C07K14/61;C07K14/65;(IPC1-7):C12N15/62;C07K19/00;C12P21/02;A61K38/27;A61K38/30 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|