TRANSPLANTATION AGENT FOR HEMATOPOIETIC STEM CELL

摘要

PROBLEM TO BE SOLVED: To obtain the subject agent by including hematopoietic stem cells as an active ingredient so as to transplant donor-derived hematopoietic stem cells through portal injection and settle the problem of take-failure/rejection after a specified pretreatment for the transplantation SOLUTION: The hematopoietic stem cells are transplanted through portal injection after pretreatment for transplantation with an effective amount of irradiation for transplantation of hematopoietic stem cells as an effective ingredient and preferably the cells are also transplanted through intravenous injection in addition. The above-mentioned irradiation is preferably performed in two portions a day by whole body irradiation as a treatment for autoimmune disease and the above-mentioned hematopoietic stem cells are preferably such as bone marrow cells containing 1-2% T cells or the like.