发明名称 |
Crystals of benzimidazole derivatives and their production |
摘要 |
A substantially solvent-free and stable crystal of the compound of the formula: wherein the ring A may optionally be substituted, R1 represents hydrogen or an N-protecting group, each of R2, R3 and R4 (1) a hydrogen atom, (2) an alkyl group which may optionally be substituted with halogen atom(s) or (3) an alkoxy group which may optionally be substituted with halogen atom(s) or alkoxy; or its salt, is produced by subjecting a solvate of the compound (I) or its salt to de-solvent treatment, in an industrially advantageous method.
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申请公布号 |
US6002011(A) |
申请公布日期 |
1999.12.14 |
申请号 |
US19980009959 |
申请日期 |
1998.01.21 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
KATO, MASAYASU;ISHIDA, TORU |
分类号 |
C07D401/12;(IPC1-7):C07D401/12 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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