发明名称 |
Peripheral benzodiazepine receptor ligands |
摘要 |
Compounds which bind with high affinity to peripheral benzodiazepine receptors are useful as antiinflammatory agents. Such compounds include isoquinoline derivatives, such as PK 11195, and benzodiazepine derivatives such as Ro 5-4864. A method of treating an inflammatory condition in a mammal with such compounds is provided. Pharmaceutical compositions comprising such compounds are described. A method is provided for identifying compounds that are therapeutically effective for treating inflammatory conditions. |
申请公布号 |
AU7516898(A) |
申请公布日期 |
1999.12.13 |
申请号 |
AU19980075168 |
申请日期 |
1998.05.22 |
申请人 |
THE UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
PATRICK L MCGEER;J. DOUGLAS WATERFIELD;EDITH G. MCGEER;ANDIS KLEGERIS |
分类号 |
A61K45/00;A61K31/47;A61K31/472;A61K31/551;A61K31/5513;A61P19/02;A61P25/28;A61P29/00 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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