发明名称 QUINOLINE CARBOXAMIDES AS TNF INHIBITORS AND AS PDE-IV INHIBITORS
摘要 A compound of general formula (I), wherein the substituents have the meanings stated in the claims 1, can be used to treat disease states, for example disease states associated with proteins that mediate cellular activity, for example by inhibiting tumour necrosis factor and/or by inhibiting phosphodiesterase IV. Disclosed is also pharmaceutical composition containing quinoline carboxamide as an active substance.
申请公布号 SK160598(A3) 申请公布日期 1999.12.10
申请号 SK19980001605 申请日期 1997.05.20
申请人 DARWIN DISCOVERY LIMITED 发明人 DYKE HAZEL J.;MONTANA JOHN G.;LOWE CHRISTOPHER;KENDALL HANNAH J.;SABIN VERITY M.
分类号 C07D215/26;A61K31/00;A61K31/47;A61K31/472;A61K31/4725;A61K45/06;A61P43/00;C07D215/48;C07D401/12;C07D401/14;C07D417/12;(IPC1-7):A61K31/47;C07D409/12 主分类号 C07D215/26
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