| 发明名称 |
ATP-SENSITIVE POTASSIUM CHANNEL GENE-DEFECTIVE ANIMALS |
| 摘要 |
19 A Kir6.2 gene-defective, non-human mammal, a mouse in particular, its tissues and cells are provided, wherein the ATP-sensitive potassium channel Kir6.2 gene, one of the subunits of KATP channels essential for insulin secretion by pancreatic .beta.-cells, is lost from one or both of the allelic loci.
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| 申请公布号 |
CA2254178(A1) |
申请公布日期 |
1999.12.10 |
| 申请号 |
CA19982254178 |
申请日期 |
1998.12.17 |
| 申请人 |
JCR PHARMACEUTICALS CO., LTD.;SEINO, SUSUMU |
发明人 |
MIYAZAKI, JUNICHI;MIKI, TAKASHI;SEINO, SUSUMU |
| 分类号 |
A01K67/027;A01K67/00;C07K14/705;C12N5/10;C12N15/09;C12N15/85;(IPC1-7):C12N5/10 |
主分类号 |
A01K67/027 |
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