发明名称 NITRIC OXIDE SYNTHASE INHIBITORS
摘要 <p>The present invention relates to novel amidino compounds of formula (I), or a salt, solvate, or physiologically functional derivative thereof; wherein R1 is selected from C1-4 alkyl, C3-4 cycloalkyl, C1-4 hydroxyalkyl, and C1-4 haloalkyl; to a process for their manufacture, to pharmaceutical composition s containing them, and to their use in therapy, in particular their use as selective inhibitors of inducible nitric oxide synthase.</p>
申请公布号 CA2333322(A1) 申请公布日期 1999.12.09
申请号 CA19992333322 申请日期 1999.05.27
申请人 GLAXO GROUP LIMITED 发明人 KLEANTHOUS, SAVVAS;YOUNG, ROBERT JOHN;BESWICK, PAUL JOHN
分类号 A61P1/00;A61K;A61K31/13;A61K31/155;A61K31/195;A61K31/197;A61K31/198;A61P1/04;A61P9/00;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P19/02;A61P25/00;A61P25/06;A61P29/00;A61P31/04;A61P37/00;A61P43/00;C07C;C07C61/04;C07C321/00;C07C323/00;C07C323/58;(IPC1-7):C07C323/58 主分类号 A61P1/00
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