发明名称 |
RECOMBINANT VENEZUELAN EQUINE ENCEPHALITIS VIRUS VACCINE |
摘要 |
A prophylactic or therapeutic vaccine for use in protecting mammals such as humans or animals against Venezelan Equine Encephalitis virus (VEE) is described. In particular, the vaccine comprises a recombinant virus such as a recombinant vaccinia virus which is able to express the structural genes of VEE in attenuated form, which has been modified to increase the protective effect of the vaccine. This is achieved by modifying the sequence of the attenuated VEE strain and/or putting this under the control of modified promoter which increases expression from the vector. Formulations of the vaccine as well as methods of treatment using the vaccine are also described .
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申请公布号 |
CA2329133(A1) |
申请公布日期 |
1999.12.09 |
申请号 |
CA19992329133 |
申请日期 |
1999.05.05 |
申请人 |
THE SECRETARY OF STATE FOR DEFENCE |
发明人 |
BENNETT, ALICE MARIE |
分类号 |
A61K39/00;A61P31/12;C07K14/18;(IPC1-7):C12N15/63;A61K39/12;A61K39/295 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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