The invention relates to genetically manipulated animals that are deficient in the expression of Caspase-9, a protein involved in programmed cell death. The invention further relates to methods for preventing specific types of cell death associated with Caspase-9 activation.
申请公布号
WO9963097(A2)
申请公布日期
1999.12.09
申请号
WO1999US11861
申请日期
1999.05.28
申请人
VERTEX PHARMACEUTICALS INCORPORATED;YALE UNIVERSITY;KUIDA, KEISUKE;FLAVELL, RICHARD, A.