发明名称 |
NITRIC OXIDE SYNTHASE INHIBITORS |
摘要 |
<p>The present invention relates to novel amidino compounds of formula (I), or a salt, solvate, or physiologically functional derivative thereof; wherein R<1> is selected from C1-4 alkyl, C3-4 cycloalkyl, C1-4 hydroxyalkyl, and C1-4 haloalkyl; to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use as selective inhibitors of inducible nitric oxide synthase.</p> |
申请公布号 |
WO9962875(A1) |
申请公布日期 |
1999.12.09 |
申请号 |
WO1999EP03583 |
申请日期 |
1999.05.27 |
申请人 |
GLAXO GROUP LIMITED;BESWICK, PAUL, JOHN;KLEANTHOUS, SAVVAS;YOUNG, ROBERT, JOHN |
发明人 |
BESWICK, PAUL, JOHN;KLEANTHOUS, SAVVAS;YOUNG, ROBERT, JOHN |
分类号 |
A61P1/00;A61K;A61K31/13;A61K31/155;A61K31/195;A61K31/197;A61K31/198;A61P1/04;A61P9/00;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P19/02;A61P25/00;A61P25/06;A61P29/00;A61P31/04;A61P37/00;A61P43/00;C07C;C07C61/04;C07C321/00;C07C323/00;C07C323/58;(IPC1-7):C07C323/58 |
主分类号 |
A61P1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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