发明名称 AZA-HETEROCYCLIC COMPOUNDS USED TO TREAT NEUROLOGICAL DISORDERS AND HAIR LOSS
摘要 The present invention is directed to novel carboxylic acids and isosteres of heterocyclic ring compounds of formula (I) which have multiple heteroatoms within the heterocyclic ring, novel derivatives containing N-linked diketos, sulfonamides, ureas and carbamates attached thereto, their preparation and use for treating neurological disorders including physically damaged nerves and neurodegenerative diseases, as well as for treating alopecia and promoting hair growth. A, X, Y, Z, D and n are as defined in the application.
申请公布号 WO9962888(A1) 申请公布日期 1999.12.09
申请号 WO1998US25574 申请日期 1998.12.03
申请人 GUILFORD PHARMACEUTICALS INC.;AMGEN, INC. 发明人 HAMILTON, GREGORY, S.;NORMAN, MARK, H.;WU, YONG-QIAN;LI, JIA-HE;STEINER, JOSEPH, P.
分类号 C07D233/02;A61K31/40;A61K31/4164;A61K31/4178;A61K31/421;A61K31/422;A61K31/426;A61K31/427;A61K31/4427;A61K31/4439;A61K31/445;A61K31/496;A61K31/505;A61K31/506;A61K31/535;A61K31/5355;A61K31/5377;A61K31/54;A61K31/541;A61K31/55;A61K31/551;A61P21/02;A61P25/00;A61P25/16;A61P25/28;C07D207/08;C07D207/16;C07D207/48;C07D211/60;C07D239/04;C07D263/04;C07D265/06;C07D277/02;C07D277/04;C07D277/06;C07D279/06;C07D401/12;C07D403/04;C07D403/12;C07D413/12;C07D417/04;C07D417/12 主分类号 C07D233/02
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