摘要 |
<p>A process for producing highly pure trifluoro methylthiomethyl benzene derivatives, which are useful as intermediates in synthesizing drugs and pesticides, at a high yield by using readily available materials without resort to flon. This method comprises treating a halogenated benzyl derivative represented by general formula (1), with thiophosgene and potassium fluoride to give a trifluoro methylthiomethyl benzene derivative represented by general formula (2), wherein R represents halogeno, cyano, nitro, benzoyl, etc.; n is an integer of 1 to 5; and X represents halogeno, alkylsulfonyloxy, arylsulfonyloxy, etc.</p> |