| 摘要 |
Production of arylalkene or conjugated diene compounds (I) comprises reacting an aryl or vinyl halide or sulfonate (II) with an olefin (III) in the presence of a catalyst comprising (a) a zero-valent palladium complex or a divalent palladium salt and (b) a phosphite ligand. Production of arylalkene or conjugated diene compounds of formula (I) comprises reacting an aryl or vinyl halide or sulfonate of formula (II) with an olefin of formula (III) in the presence of a catalyst comprising: (a) a zero-valent palladium complex or a divalent palladium salt; and (b) a phosphite ligand of formula (IVa) or (IVb). A = Ar or a group of formula (i)-(iii): R<1>-R<3> = H, Y, CN, COOH, COOY, COY, Z, COOZ, COZ, OY, OCOY or NY2; Y = 1-8C alkyl; Z = 6-10C aryl optionally substituted by 1-5 of Y, OY, OCOY, OPh, Ph, aryl, F, Cl, OH, NO2, SiY3, CN, COOH, CHO, SO3H, NH2, NHY, NY2, PY2, SO2Y', SOY', CF3, NHCOY, COOY, CONH2, COY, NHCHO, NHCOOY, COPh, COOPh, CH=CHCOOY, PPh2, CH=CHCOOH, POPh2, POY2, PO3H2, PO(OY')2 or SO3Y; Y' = 1-6C alkyl; Y = 1-4C alkyl; R1a-R7a = H, Y, OY, OCOY, OPh, Ph, aryl, F. Cl, OH, NO2, SiY3, CN, COOH, CHO, SO3H, NH2, NHY, NY2, PY2, SO2Y', SOY', CF3, NHCOY, COOY, CONH2, COY, NHCHO, NHCOOY, COPh, COOPh, CH=CHCOOY, PPh2, CH=CHCOOH, POPh2, POY2, PO3H2, PO(OY')2 or SO3Y; Ar = 5- to 7-membered N-, O- or S-containing heteroaryl optionally fused to aromatic, heteroaromatic and/or alicyclic rings and optionally substituted by Y, aryloxy, aryl, F, Cl, OH, NO2, CN, COOH, CHO, SO3H, NH2, NHY asterisk , NY asterisk 2, CH=CHCOOH, NHCOY asterisk , COY asterisk , NHCHO, COZ, COOZ, CF3, CONH2, POZ2, POY asterisk 2, SiY asterisk 3, OY, OCOY, OPh, Ph, NHY, COOY, NHCOOY, COPh, COOPh, CH=CHCOOY, POPh2, PO3H2, SO3Y and/or SO2Y; Y asterisk = 1-12C alkyl; R8a-R10a = H, CN, COOH, COOY, CONH2, CONHY, CONY2, F, COOPh, Y, Ph, aryl, POPh2, POY2, COPh, COY, OY, CONHY, CONY2, NHY, PO3H2, SO3H, SO3Y, SO2Y or OPh; X = I, Br, Cl, OSO2CF3, OSO2Ph, tosyloxy or OSO2Y; R11a-R14a = 1-18C alkyl optionally substituted by OY, OCOY, OPh, Ph, F, Cl, OH, NO2, CN, COOH, CHO, SO3H, SO2Y, SOY, NH2, NHY, NY2, NHCOY, CF3, COOY, CONH2, COY, NHCHO, NHCOOY, COPh, COOPh, CH=CHCOOY, CH=CHCOOH, POPh2 or POY2; or Ar'; Ar' = phenyl, naphthyl, anthryl, phenanthryl, biphenylyl or heteroaryl (5- to 7-membered, containing N, O or S) optionally substituted by 1-10 of Y, OAr', Ar', F, Cl, OH, CN, COOH, CHO, SO3H, NH2, NHY asterisk , NY asterisk 2, NHCOY asterisk , COY asterisk , NHCHO, COAr', CO2Ar', CF3, CONH2, CH=CHCOOH, POAr'2, POY asterisk 2, SiY asterisk 3, OY, OCOY, OPh, Ph, COOY, NHCOOY, COPh, COOPh, CH=CHCOOY, POPh2, PO3H2, SO3Y, SO2Y or SOY.
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