| 发明名称 |
ENHANCED CIRCULATION EFFECTOR COMPOSITION AND METHOD |
| 摘要 |
A liposome composition comprising small, surface-bound effector surface-bound is disclosed. The liposomes have a surface layer of hydrophilic polymer chains, for enhanced circulation time in the bloodstream. The effector molecules are attached to the distal ends of the polymer chains. In one embodiment, the effector is polymyxin B, for treatment of septic shock.
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| 申请公布号 |
CA2157410(C) |
申请公布日期 |
1999.12.07 |
| 申请号 |
CA19942157410 |
申请日期 |
1994.03.22 |
| 申请人 |
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发明人 |
ZALIPSKY, SAMUEL;WOODLE, MARTIN C.;MARTIN, FRANCIS J.;BARENHOLZ, YECHEZKEL |
| 分类号 |
A61K9/127;A61K31/715;A61K38/00;A61K38/21;A61K38/22;A61K39/395;A61K47/48;A61P5/18;A61P7/00;A61P9/00;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P35/04;A61P37/06;A61P43/00;(IPC1-7):A61K9/127 |
主分类号 |
A61K9/127 |
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