发明名称 |
Photosensitive caged macromolecules |
摘要 |
Disclosed is a method for preparing a photosensitive peptide which is capable of being activated or deactivated in a biological system, including the steps of: (a) providing an amino acid including a photolabile molecule; and (b) incorporating the amino acid into a peptide during synthesis, wherein incorporation of the amino acid into the peptide produces a photosensitive peptide. Also disclosed is a method of introducing a photosensitive cleavage site into a synthetic peptide, including synthesizing a synthetic peptide having at least one photolabile amino acid, wherein the photolabile amino acid is positioned within the synthetic peptide so that upon irradiation the synthetic peptide is cleaved.
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申请公布号 |
US5998580(A) |
申请公布日期 |
1999.12.07 |
申请号 |
US19950542927 |
申请日期 |
1995.10.13 |
申请人 |
FAY, FREDERICK F.;CARRAWAY, ROBERT;IKEBE, MITSUO;WALKER, JEFFREY |
发明人 |
FAY, FREDERICK F.;CARRAWAY, ROBERT;IKEBE, MITSUO;WALKER, JEFFREY |
分类号 |
C07K1/00;C07K1/107;(IPC1-7):A61K38/00;G01N33/00;G01N33/543 |
主分类号 |
C07K1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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