发明名称 |
Methods of modulating serine/threonine protein kinase function with azabenzimidazole-based compounds. |
摘要 |
The present invention is directed in part towards methods of modulating the function of serine/threonine protein kinases with azabenzimidazole-based compounds. The methods incorporate cells that express a serine/threonine protein kinase, such as RAF. In addition, the invention describes methods of preventing and treating serine/threonine protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to azabenzimidazole compounds and pharmaceutical compositions comprising these compounds. |
申请公布号 |
ZA9808797(B) |
申请公布日期 |
1999.12.02 |
申请号 |
ZA19980008797 |
申请日期 |
1998.09.25 |
申请人 |
ASTA MEDICA AKTIENGESELLSCHAFT |
发明人 |
GERALD MCMAHON;HEINZ WEINBERGER;BERNHARDT KUTSCHER;HARALD APP |
分类号 |
C12Q1/48;A61K31/415;A61K31/435;A61K31/4353;A61K31/437;A61P35/00;A61P43/00;C07D;C07D471/04 |
主分类号 |
C12Q1/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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