| 摘要 |
<p>The invention concerns a highly region-selective method for preparing a cyclodextrin C-6 monosulphonyl derivative in particular β-cyclodextrin, which consists in reacting said cyclodextrin with a sulphonylation agent in an aqueous alkaline solution in the presence of a metal salt capable of forming a co-ordinating complex with the cyclodextrin secondary hydroxyl groups, and at the end of the reaction in recuperating said cyclodextrin C-6 monosuphonyl derivative from the reaction mixture. Cyclodextrin monosulphonyl derivatives are particularly useful as starting materials for obtaining monofunctionalised cyclodextrin derivatives.</p> |
