发明名称 |
HETEROCYCLIC INDOLE DERIVATIVES AND MONO- OR DIAZAINDOLE DERIVATIVES |
摘要 |
Indole derivatives and mono- or diazaindole derivatives represented by general formula (1), pharmaceutically acceptable acid-addition salts or base-addition salts thereof or hydrates of the same which have a COX-2 inhibitory activity and are useful as drugs such as anti-inflammatory agents, wherein Het represents an optionally substituted heterocycle; A1 and A2 independently represent each -CH=, etc.; A3 represents -CH2-, etc.; R1 represents 4-fluorophenyl, etc.; R2 represents alkyl; and n is 0, 1 or 2, provided that when A1 and A2 are both -CH=, then A3 is -CH2- or -SO2-.
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申请公布号 |
WO9961436(A1) |
申请公布日期 |
1999.12.02 |
申请号 |
WO1999JP02718 |
申请日期 |
1999.05.25 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA;MATSUOKA, HIROHARU;KATO, NOBUAKI;TAKAHASHI, TADAKATSU;MARUYAMA, NORIAKI;ISHIZAWA, TAKENORI;SUZUKI, YUKIO |
发明人 |
MATSUOKA, HIROHARU;KATO, NOBUAKI;TAKAHASHI, TADAKATSU;MARUYAMA, NORIAKI;ISHIZAWA, TAKENORI;SUZUKI, YUKIO |
分类号 |
A61P29/00;A61P43/00;C07D401/04;C07D401/06;C07D403/04;C07D405/04;C07D405/06;C07D413/04;C07D417/04;C07D417/06;C07D471/04;C07D487/04;(IPC1-7):C07D401/04;A61K31/40;A61K31/41;A61K31/42;A61K31/435;A61K31/44;A61K31/495 |
主分类号 |
A61P29/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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