发明名称 |
PROCESS FOR PRODUCING COMPOSITE PREPARATION CONTAINING NUCLEIC ACID |
摘要 |
A process for producing a homogeneous nucleic-acid-containing composite preparation of good quality which is capable of sterilization by filtration and is characterized by containing no coarse particles having a size of 7 mu m or larger, which are regarded as unsafe for the human body. The process for producing the preparation, containing a composite of a cationic carrier with a nucleic acid polymer, is characterized in that two single-stranded nucleic acid polymers capable of at least partly forming a double-stranded state are separately added, each in the single-stranded state, to either a cationic carrier or a material from which the cationic carrier is to be formed, and all these ingredients are subjected to a dispersing treatment.
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申请公布号 |
WO9961032(A1) |
申请公布日期 |
1999.12.02 |
申请号 |
WO1999JP02713 |
申请日期 |
1999.05.24 |
申请人 |
NIPPON SHINYAKU CO., LTD.;SUGIHARA, KATSUHIRO;SEKI, JUNZO;HIRABAYASHI, KAZUKO |
发明人 |
SUGIHARA, KATSUHIRO;SEKI, JUNZO;HIRABAYASHI, KAZUKO |
分类号 |
A61K31/7105;A61K9/19;A61K31/70;A61K31/7088;A61K31/711;A61K31/712;A61P35/00;(IPC1-7):A61K31/70;A61K47/16;A61K47/24;A61K9/10 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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