发明名称 |
Gene therapy using stromal cells |
摘要 |
A method of causing production and secretion into the bloodstream of a human patient of a biologically active enzyme for which the human patient suffers a deficiency; the method involves introducing into the human patient donor bone marrow stromal cells which have been transfected with a gene encoding the enzyme, so that the introduced cells can adhere to a bone cavity surface of the patient and produce and secrete the active enzyme.
|
申请公布号 |
US5993801(A) |
申请公布日期 |
1999.11.30 |
申请号 |
US19970914631 |
申请日期 |
1997.08.19 |
申请人 |
ALG COMPANY |
发明人 |
GREENBERGER, JOEL S.;LEVINE, PETER H. |
分类号 |
A61K48/00;A01N63/00;A61K38/00;A61K38/18;A61K38/37;A61P7/00;C07K14/495;C07K14/71;C07K14/755;C12N15/09;(IPC1-7):A01N63/00 |
主分类号 |
A61K48/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|