| 发明名称 |
NEW PROCESS FOR PREPARING (-)-TRANS-N-p-FLUOROBENZOYLMETHYL-4-(p-FLUOROPHENYL)-3- 3,4-(METHYLENEDIOXY)PHENOXY]METHYL]-PIPERIDINE |
| 摘要 |
<p>PCT No. PCT/EP97/01007 Sec. 371 Date Oct. 27, 1997 Sec. 102(e) Date Oct. 27, 1997 PCT Filed Feb. 28, 1997 PCT Pub. No. WO97/31915 PCT Pub. Date Sep. 4, 1997The process consists of reacting (-)trans-N-p-fluorophenyl)-3-[[3,4-(methylenedioxy)phenoxy]methyl]-piperidine acetate with 2-chloro- or 2-bromo-4'-fluoroacetophenone. The resulting compound can be isolated as a pharmaceutically acceptable addition salt by reaction with the corresponding acid.</p> |
| 申请公布号 |
GR3030683(T3) |
申请公布日期 |
1999.11.30 |
| 申请号 |
GR19990401765T |
申请日期 |
1999.07.05 |
| 申请人 |
FERRER INTERNACIONAL, S.A. |
发明人 |
FOGUET, RAFAEL;GUBERT, SANTIAGO;SACRISTAN, AURELIO;ORTIZ, JOSE A. |
| 分类号 |
A61K31/443;A61K31/445;C07D405/12;(IPC1-7):C07D405/12 |
主分类号 |
A61K31/443 |
| 代理机构 |
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