发明名称 |
Thia-isochromene-dioxide derivs anti- |
摘要 |
Therapeutic intermediates exhibiting also anti-convulsive properties in animal experiments, consist of 3-carboxy-1-thia-isochroman-1,1-di oxide derivs. (I): (where R1 and R2 are lower alkyl and R3 is H or alkyl). Prepd. (a) by reacting cpds. (II): (where R4 is -COOH, carboxylate, carbamoyl or carbonitrile and Hal is halogen) with conc. H2SO4 at room temp., diluting and heating for example to 70-90 degrees C or (b) by saponifying 3-carbamoyl- or 3-carboxylate derivs. of (I) in diluted inorganic acids, such as HCl or H2SO4.
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申请公布号 |
CH531529(A) |
申请公布日期 |
1972.12.15 |
申请号 |
CH19720012225 |
申请日期 |
1970.03.17 |
申请人 |
VEB ARZNEIMITTELWERK DRESDEN |
发明人 |
POEPEL,WERNER;FAUST,GOTTFRIED;FIEDLER,WERNER;DIETZ,GUENTHER |
分类号 |
A61K31/39;C07D327/06;(IPC1-7):C07D89/12 |
主分类号 |
A61K31/39 |
代理机构 |
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地址 |
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