Bis(ortho-diarylphosphinophenyl)-tetrahydro-bi(1,3-oxazole) and a preparation method thereof

摘要

The present invention relates to optically pure bis(o-diarylphosphinophenyl)-tetrahydro-bi(1,3-oxazole) compounds represented by the formula (I) and a preparation method thereof. Bis(o-diarylphosphinophenyl)-tetrahydro-bi(1,3-oxazole) compounds of the present invention include (4S,4'S)-2,2'-bis(o-diarylphosphinophenyl)-4,4',5,5'-tetrahydro-4,4'-bi(1,3-oxazole) represented by the formula (Ia) and its enantiomer, (4R,4'R)-2,2'-bis(o-diarylphosphinophenyl)-4,4',5,5'-tetrahydro-4,4'-bi(1,3-oxazole) represented by the formula. The compounds of the present invention can be utilized in asymmetric hydrosilylation, hydrogenation, cyclopropylation and alkylation reactions.