发明名称 3-spiro-indolin-2-one derivatives as vasopressin and/or oxytocin receptor ligands
摘要 PCT No. PCT/FR96/01666 Sec. 371 Date Apr. 17, 1998 Sec. 102(e) Date Apr. 17, 1998 PCT Filed Oct. 24, 1996 PCT Pub. No. WO97/15556 PCT Pub. Date May 1, 1997The subject of the invention is indolin-2-one derivatives of formula: in which: W represents a -CH2- or -SO2- group; Cy forms, with the carbon to which it is bonded, a non-aromatic, saturated or unsaturated C3-C12 hydrocarbon ring which is optionally condensed or substituted by one or a number of (C1-C7)alkyl groups, it being possible for the said groups to substitute the same carbon atom one or a number of times, or by a C3-C6 spirocycloalkyl; T represents a (C1-C4)alkylene which is optionally interrupted by a (C3-C6)cycloalkylene, the said alkylenes optionally being substituted one or a number of times on the same carbon atom by a (C1-C3)alkyl; or alternatively T represents a direct bond; Z represents in particular an amino group; R1 and R2, as well as R3 and R4, are either hydrogen or substituents, such as, for example, a halogen, an alkyl, and the like.
申请公布号 US5994350(A) 申请公布日期 1999.11.30
申请号 US19980051900 申请日期 1998.04.17
申请人 SANOFI-SYNTHELABO 发明人 FOULON, LOIC;GARCIA, GEORGES;SERRADEIL-LE GAL, CLAUDINE;VALETTE, GERARD
分类号 C07D209/54;A61K31/40;A61K31/403;A61K31/404;A61K31/4427;A61K31/445;A61K31/454;A61K31/496;A61K31/535;A61K31/5377;A61K31/541;A61K45/00;A61P1/00;A61P1/04;A61P1/16;A61P3/10;A61P5/00;A61P7/04;A61P7/10;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P11/00;A61P13/12;A61P15/00;A61P25/00;A61P25/06;A61P25/18;A61P25/22;A61P25/28;A61P25/30;A61P25/34;A61P27/02;A61P27/06;A61P27/12;A61P35/00;A61P43/00;C07D209/96;C07D401/12;C07D403/12;C07D413/12;(IPC1-7):A61K31/40;C07D209/06 主分类号 C07D209/54
代理机构 代理人
主权项
地址
您可能感兴趣的专利