发明名称 DERIVATI DELLA 5'-DEOSSI-CITIDINA
摘要 <p>Novel 5'-deoxy-cytidine derivatives represented by the general formula (I) wherein R1 is a hydrogen atom or a group easily hydrolyzable under physiological conditions; R2 is a hydrogen atom, or -CO-OR4 group [wherein R4 is a saturated or unsaturated, straight or branched hydrocarbon group consisting of one to fifteen carbon atoms, or a group of the formula -(CH2)n-Y (in which Y is cyclohexyl or phenyl; n is an integer from 0 to 4)]; R3 is a hydrogen atom, bromo, iodo, cyano, a C1-4 alkyl group [which may be substituted with halogen atom(s)], a vinyl or ethynyl group [which may be substituted with halogen atom(s), C1-4 alkyl, cycloalkyl, aralkyl, or aromatic ring which may have one or more hetero atom(s)], or an aralkyl group which may be substituted for use in medical therapy, especially tumor therapy.</p>
申请公布号 ITMI981196(A1) 申请公布日期 1999.11.29
申请号 IT1998MI01196 申请日期 1998.05.29
申请人 F.HOFMMANN-LA ROCHE AG 发明人 HATTORI KAZUO;ISHIKAWA TOHRU;ISHITSUKA HIDEO;KOHCHI YASUNORI;OIKAWA NOBUHIRO;SHIMMA NOBUO;SUDA HITOMI
分类号 C07H19/067;A01N43/04;A61K31/505;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7068;A61K31/7072;A61P35/00;A61P43/00;C07D239/553;C07H19/06 主分类号 C07H19/067
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