发明名称 |
Intermediates of camptothecin (CPT-11) or mappicine and their manufacture |
摘要 |
Various intermediates as defined in the specification for preparing camptothecin derivatives, other compounds related to the synthesis of CPT-11 of formula (I) and compounds related to mappicine of formula (II) are claimed. The intermediates are based on 4-keto-pyridine, 2-pyridine-1,3-dioxolane, pyrano[3,4-c]pyridine, pyrano[3,4-c]indolizine or indolizine or on a compound of formula II. Also claimed are the processes for preparing the above compounds.
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申请公布号 |
NZ306664(A) |
申请公布日期 |
1999.11.29 |
申请号 |
NZ19960306664 |
申请日期 |
1996.04.01 |
申请人 |
PHARMACIA & UPJOHN COMPANY |
发明人 |
HENEGAR, KEVIN E;SIH, JOHN C |
分类号 |
C07D491/147;A61K31/435;A61K31/436;A61K31/4738;A61P35/00;C07C251/26;C07C271/44;C07D213/30;C07D213/61;C07D213/64;C07D213/643;C07D213/79;C07D405/04;C07D471/04;C07D471/14;C07D491/04;C07D491/052;C07D491/14;C07D491/22;(IPC1-7):A61K31/44;C07D213/74 |
主分类号 |
C07D491/147 |
代理机构 |
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地址 |
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