摘要 |
<p>Present invention is based on the discovery and isolation of the dissatisfaction (DSF) gene and its protein product. An isolated polynucleotide encoding DSF, substantially pure DSF polypeptide, and an antibody that binds to DSF polypeptide are provided. Also provided are: a DNA construct that comprises a disrupted DSF gene which can prevent functional DSF expression, a transgenic insect having a transgene disrupting DSF expression, a method of producing transgenic insect comprising DSF gene, and a method of identifying a compound that affects the activity of a DSF polypeptide.</p> |