COMPOUNDS, SCREENING METHODS, AND USES INVOLVING ANTI-APOPTOTIC GENES AND GENE PRODUCTS

摘要

Novel polypeptides having anti-apoptotic activity, and methods of screening for such novel polypeptides having anti-apoptotic activity, and polynucleotides encoding such polypeptides; compounds that regulate or modulate apoptosis and/or anti-apoptotic activity, such as compounds having anti-apoptotic activity, and such as compounds that induce, restore, or modulate apoptosis and/or inhibit, diminish, or modulate anti-apoptotic activity, methods of screening for such compounds, and methods of using such compounds in the therapeutic treatment of diseases; methods of treating eukaryotic cells with compounds that regulate or modulate apoptosis and/or anti-apoptotic activity; methods of enhancing the stability, growth, and/or productivity of eukaryotic cells; pharmaceutical compositions that regulate or modulate apoptosis and/or anti-apoptotic activity.