摘要 |
<p>3-Substituted 5-aryl-4-isoxazolecarbonitriles of formula (I) wherein (R=H, halogen, COOH, COOR'', alkyl, alkoxy, NO2, OR'', phenyl; R'=alkyl, COOH, COOR''; R''=alkyl; X=O or S or a single bond; n=1-6) proved to be active, at non-cytotoxic doses, against a series of viruses (Polio 1, ECHO 9, Coxsackie B1, Rhinovirus, Measles).</p> |