发明名称 Process for the preparation of a pharmaceutical intermediate
摘要 The invention relates to a process for the preparation of (+/-)-4-(S,R)- [(3,4-dichlorophenyl) -3,4-dihydro-1(2H) -naphthalene-1-ylidene] -methylamine of Formula (I) by reacting 4-(3,4-dichlorophenyl) -3,4-dihydro-1(2H) -naphthalene-1-one of Formula (II) with methyl amine which comprises carrying out the reaction in the absence of a dehydrating agent, in a lower alkanol. The compound of Formula (I) is a useful pharmaceutical intermediate.
申请公布号 AU3840199(A) 申请公布日期 1999.11.23
申请号 AU19990038401 申请日期 1999.05.03
申请人 EGIS GY¤GYSZERGYAR RT. 发明人 GYULA SIMIG;PETER K¤TAY NAGY;JOZSEF BARK¤CZY;GYORGY KRASZNAI;KALMAN NAGY;GYORGYI VERECZKEYNE DONATH;NORBERT NEMETH;TIBOR SZAB¤;ILONA SZTRUHAR;LASZLO LADANYI;LASZLO BALAZS;IMRE DOMAN;ZOLTAN GREFF;ZOLTAN RATKAI;PETER SERES
分类号 C07C249/02;C07C251/20 主分类号 C07C249/02
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