发明名称 Method for treating tumors having high LDL requirements employing MTP inhibitors
摘要 A method is provided for treating hematologic tumors and solid tumors, including certain types of leukemias and metastatic tumors, having high LDL requirements employing a delipidating agent such as an MTP inhibitor to substantially reduce LDL blood levels. In addition, a method is provided for treating tumors of the above types having high LDL requirements, especially hematologic tumors such as certain leukemias, employing a delipidating compound to substantially remove native LDL, and then administering a cytotoxic agent carried in reconstituted LDL.
申请公布号 US5990110(A) 申请公布日期 1999.11.23
申请号 US19970914062 申请日期 1997.07.15
申请人 BRISTOL-MEYERS SQUIBB COMPANY 发明人 FIRESTONE, RAYMOND A.
分类号 A61K31/00;A61K31/4468;A61K31/454;(IPC1-7):A61K31/495;A61K31/445 主分类号 A61K31/00
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