发明名称 |
Benzopyran derivatives having leukotriene-antagonistic action |
摘要 |
PCT No. PCT/EP97/01418 Sec. 371 Date Oct. 15, 1998 Sec. 102(e) Date Oct. 15, 1998 PCT Filed Mar. 20, 1997 PCT Pub. No. WO97/34885 PCT Pub. Date Sep. 25, 1997The present invention relates to novel 4-oxo-4H-1-benzopyran compounds containing benzyloxymethyl, 3-phenylpropyl, or other araliphatic substituents in their 8-position. These compounds show a leukotriene-antagonistic activity. The compounds are characterized by good oral adsorption. The compounds of the present invention may be used as anti-inflammatory and antiallergic medicaments, and in the treatment of cardiovascular diseases.
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申请公布号 |
US5990142(A) |
申请公布日期 |
1999.11.23 |
申请号 |
US19980142922 |
申请日期 |
1998.10.15 |
申请人 |
LABORATORIOS MENARINI S.A. |
发明人 |
CARGANICO, GERMANO;CASELLAS, DAVID MAULEON;AVELLANA, JAIME PASCUAL;GARCIA PEREZ, M. LUISA;BENET, ALBERT PALOMER |
分类号 |
C07D311/54;A61K31/00;A61K31/35;A61K31/352;A61K31/353;A61K31/41;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P17/06;A61P19/00;A61P25/00;A61P27/00;A61P27/14;A61P29/00;A61P37/00;A61P37/08;A61P43/00;C07C45/54;C07C205/45;C07D311/24;C07D311/58;C07D405/04;C07D405/12;C07D405/14;C07D407/06;C07D407/12;(IPC1-7):A61K31/35 |
主分类号 |
C07D311/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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