发明名称 |
Use of 5HT4 receptor antagonists for overcoming gastrointestinal effects of serotonin reuptake inhibitors |
摘要 |
PCT No. PCT/EP97/00586 Sec. 371 Date Aug. 11, 1998 Sec. 102(e) Date Aug. 11, 1998 PCT Filed Feb. 7, 1997 PCT Pub. No. WO97/29739 PCT Pub. Date Aug. 21, 1997The present invention concerns the use of receptor antagonists of the 5HT4 receptor for avoiding, alleviating, suppressing or overcoming the gastrointestinal side-effects of serotonin reuptake inhibitors. The present invention also concerns pharmaceutical formulations comprising 5HT4-receptor antagonists for alleviating, suppressing or overcoming the gastrointestinal side-effects of serotonin reuptake inhibitors, as well as pharmaceutical compositions comprising 5HT4 receptor antagonists and serotonin reuptake inhibitors.
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申请公布号 |
US5990159(A) |
申请公布日期 |
1999.11.23 |
申请号 |
US19980117974 |
申请日期 |
1998.08.11 |
申请人 |
JANSSEN PHARMACEUTICA, N.V. |
发明人 |
MEULEMANS, ANN LOUISE GABRIELLE;BOSMANS, JEAN-PAUL RENEMARIE ANDRE |
分类号 |
A61K45/00;A61K31/00;A61K31/437;A61K31/4453;A61K31/453;A61K31/454;A61K31/46;A61K45/06;A61P1/00;A61P25/24;A61P43/00;(IPC1-7):A61K31/34;A61K31/135 |
主分类号 |
A61K45/00 |
代理机构 |
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