| 摘要 |
PCT No. PCT/KR97/00073 Sec. 371 Date Oct. 21, 1998 Sec. 102(e) Date Oct. 21, 1998 PCT Filed Apr. 30, 1997 PCT Pub. No. WO97/42186 PCT Pub. Date Nov. 13, 1997The present invention relates to a process for preparation of 5,6-dimethyl-2-(4-fluorophenyl-amino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine represented by the following formula (I), and its acid addition salts by reacting a pyrimidine derivative represented by the formula (II-A), in which Hal represents a halogen, with 1-methyl-1,2,3,4-tetrahydroisoquinoline represented by the formula (III),
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