| 发明名称 |
Materials and methods for detection and treatment of insulin-dependent diabetes |
| 摘要 |
The method and compositions of this invention provide an effective and reliable substitute for the currently employed ICA assay for diabetes. By providing a method for detecting autoantibodies to GAD65, IA-2 and a previously unidentified antigen termed IA-2 beta herein, the method provides a chemical assay which has improved reliability. In addition, these antigens may be employed in therapeutic regimens aimed at achieving amelioration of the clinical condition.
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| 申请公布号 |
US5989551(A) |
申请公布日期 |
1999.11.23 |
| 申请号 |
US19950548159 |
申请日期 |
1995.10.25 |
| 申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES;THE UNIVERSITY OF FLORIDA |
发明人 |
MACLAREN, NOEL K.;NOTKINS, ABNER L.;LAN, MICHAEL S.;LI, QING |
| 分类号 |
A61K38/00;A61K39/00;A61P3/10;A61P37/02;C07K14/47;C07K14/705;C12N9/16;(IPC1-7):A61K39/00 |
主分类号 |
A61K38/00 |
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