发明名称 |
(-)-RITODRINE |
摘要 |
(-)-Ritodrine, that is (-)-erythro-1-(p-hydroxyphenyl)-2-¢2-(p-hydroxyphenyl)ethylamino)-1-propanol or a salt thereof substantially free from the (+)-isomer is disclosed. The compound has a strong suppressive effect on uterine contraction in comparison with (~)-ritodrine and (+)-ritodrine and has the same level of toxicity as these compounds, so that it can be used as a therapeutic agent of threatened premature birth and threatened abortion as well as a therapeutic agent of dysmenorrhea having a high safety.
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申请公布号 |
CA2116685(C) |
申请公布日期 |
1999.11.23 |
申请号 |
CA19932116685 |
申请日期 |
1993.06.30 |
申请人 |
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发明人 |
YAMAZAKI, NAOKI;FUKUDA, YOSHIMASA;SHIBAZAKI, YOSHIAKI;NIIZATO, TETSUTAROU;KOSUGI, ISAO;YOSHIOKA, SHIN |
分类号 |
A61K31/135;C07B53/00;C07C213/00;C07C215/60;(IPC1-7):C07C215/60 |
主分类号 |
A61K31/135 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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