发明名称 |
GROWTH DIFFERENTIATION FACTOR-9 REGULATORY SEQUENCES AND USES THEREFOR |
摘要 |
Isolated GDF-9 regulatory sequences are disclosed, as well as methods of using the sequences to modulate tissue-specific expression of genes. The GDF-9 regulatory sequences include, for example, enhancer and promoter elements that naturally drive transcription of GDF-9 in specific tissues. The GDF-9 regulatory sequences can be derived from the untranscribed upstream (e.g., first 10 kilobases) and downstream regions, and transcribed, untranslated regions of a GDF-9 gene. |
申请公布号 |
WO9950406(A3) |
申请公布日期 |
1999.11.18 |
申请号 |
WO1999US07185 |
申请日期 |
1999.03.31 |
申请人 |
METAMORPHIX, INC.;MATZUK, MARTIN, MATTHEW;ELVIN, JULIA, ANDREA |
发明人 |
MATZUK, MARTIN, MATTHEW;ELVIN, JULIA, ANDREA |
分类号 |
A01K67/027;C07K14/475;C12N5/10;C12N15/09;C12N15/85 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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