发明名称 HETEROCYCLIC INHIBITORS OF P38
摘要 The present invention relates to inhibitors of p38, a mammalian protein kina se involved in cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitor s. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in t he treatment and prevention of various disorders.
申请公布号 CA2331460(A1) 申请公布日期 1999.11.18
申请号 CA19992331460 申请日期 1999.05.11
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 BELLON, STEVEN;BEMIS, GUY;SALITURO, FRANCESCO;GALULLO, VINCENT;COCHRAN, JOHN
分类号 A61K31/17;A61K31/435;A61K31/44;A61K31/4418;A61K31/4427;A61K31/4439;A61K31/444;A61K31/4545;A61K31/496;A61K31/5377;A61K31/551;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P5/14;A61P7/02;A61P7/04;A61P7/06;A61P9/00;A61P9/02;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P19/08;A61P19/10;A61P21/04;A61P25/00;A61P25/04;A61P25/16;A61P25/28;A61P29/00;A61P31/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P35/02;A61P37/06;A61P37/08;C04B35/01;C07C275/32;C07D;C07D213/00;C07D213/56;C07D213/73;C07D213/74;C07D213/75;C07D401/06;C07D401/12;G02B6/02;G02B6/12;(IPC1-7):C07D213/56 主分类号 A61K31/17
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